Searchable abstracts of presentations at key conferences in endocrinology

ea0083erco1 | Endocrine-related Cancer | EYES2022

Tumor suppressor role of RBM22 in prostate cancer acting as a dual-factor regulating alternative splicing and transcription of key oncogenic genes

A. J. Montero-Hidalgo , P. Saez-Martinez , A. Sarmento-Cabral , A. S. De la Rosa-Herencia , R. Sanchez-Sanchez , T. Gonzalez-Serrano , E. Gomez-Gomez , M. D. Gahete , R. M. Luque , J. M. Jimenez-Vacas

Background: Prostate cancer (PCa) is one the leading causes of cancer-related deaths among men in developed countries. Therefore, the identification of novel molecular targets for treatment is urgently needed to improve patientsÂ’ outcomes. In this scenario, our group has recently reported that elements of the cellular machinery controlling alternative-splicing processes might be used as potential novel therapeutic tools for PCa. In this context, although RBM22 has been id...